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Search Results for " tumor cell "

ターゲット

Others

620

阻害剤

137

天然化合物

335

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T9918	Daratumumab		Others
	Daratumumab is a human monoclonal antibody that targets CD38 a cell surface protein that is overexpressed on multiple myeloma MM) cells.		Others
T9271	RAD51-IN-1		DNA/RNA Synthesis
	Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.		DNA/RNA Synthesis
T21408	DM1-SMe	DM1-SSMe	Microtubule Associated
	DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell ...		Microtubule Associated
T6393	ARQ 621		Kinesin
	ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.		Kinesin
T8668	HM03		HSP
	HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.		HSP
T12695	RBN-2397		PARP
	RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.		PARP
T21981	Phthalazinone pyrazole		Aurora Kinase
	Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.		Aurora Kinase
T5414	Glumetinib	SCC244	c-Met/HGFR
	Glumetinib (SCC244) (SCC 244) is a novel potent and selective inhibitor of c-Met kinase (IC50: 0.42 nM).		c-Met/HGFR
T4435	E7820	ER68203-00	Integrin
	E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).		Integrin
T8316	1V209	TLR7 agonist T7	TLR
	1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.		TLR
T1792L	Regorafenib monohydrate		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect...		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T12477	Uzansertib phosphate	INCB053914 phosphate	Pim
	Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).		Pim
T2394	Pixantrone dimaleate	BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate	Topoisomerase
	Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.		Topoisomerase
T8376	PKCβ inhibitor 1	KUN79359	Apoptosis , PKC
	PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively).		Apoptosis , PKC
T1950	PND-1186	PND1186,PND 1186,VS-4718,SR-2516	Apoptosis , FAK
	PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).		Apoptosis , FAK
T1792	Regorafenib	BAY 73-4506,Fluoro-Sorafenib	Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
	Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity.		Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy
T0373	Erlotinib	OSI-744,NSC 718781,CP358774,R1415	EGFR , Autophagy
	Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.		EGFR , Autophagy
T23480	U-83836E		Others
	U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.		Others
T1608	ADH-1 trifluoroacetate	Exherin trifluoroacetate	Dehydrogenase
	ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-c...		Dehydrogenase
T4235	Roblitinib	FGF-401	FGFR
	Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits the activity of FGFR4, which leads ...		FGFR
T9712	PF07104091	PF-07104091	CDK
	PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.		CDK
T16266	NAMI-A		FAK , CETP
	NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.		FAK , CETP
T6517	Golvatinib	E-7050	VEGFR , c-Met/HGFR
	Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic ...		VEGFR , c-Met/HGFR
T3352	XL413		cholecystokinin , Casein Kinase , Pim , CDK
	XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential antineoplastic activity. XL-413 binds to and inhibits the activity of CDC7, which may result in the inhibition of DNA ...		cholecystokinin , Casein Kinase , Pim , CDK
T2090	Lexibulin	CYT-997	Apoptosis , Reactive Oxygen Species , Microtubule Associated
	Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines). Lexibulin blocks the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this...
T67735	Auristatin23		Others
	Auristatin23 is an Antitumor agent. Auristatin23 exhibits antiproliferative activity on tumor cell lines.		Others
T9463	6-HYDROXYLAMINOURACIL		Others
	6-HYDROXYLAMINOURACIL is a derivative of uracil, which induces DNA damage and apoptosis in tumor cells and inhibits tumor cell growth in vitro.		Others
T3351	Onatasertib	CC223,CC 223,CC-223	Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
	Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity. Onatasertib inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor ce...		Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
T2610L	BMS-599626 2HCL(714971-09-2 Free base)	BMS 599626 dihydrochloride,BMS-599626 2HCL(714971-09-2 Free base),AC480 2HCl	HER
	BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative. BMS-599626 is an orally available and selective dual inhibitor of HER1 and HER2 with IC50s of 20 and 30 nM, respectively. BMS-599626 inhibits tumor cell proliferat...		HER
T6017	Linsitinib	OSI-906	IGF-1R
	OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...		IGF-1R
T4254	TM5441		PAI-1 , Apoptosis
	TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor 1 (PAI-1).		PAI-1 , Apoptosis
T3485	Probimane	AT-2153,MM-159	Others
	Probimane (AT-2153) had Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation in human tumor cell lines with MST-16.		Others
T78212	RMC-9805	KRAS G12D inhibitor 18,KRAS G12D IN 18	Others
	RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.		Others
T6322	Copanlisib	BAY 80-6946	Apoptosis , PI3K
	Copanlisib (BAY 80-6946) is a phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor c...		Apoptosis , PI3K
T11209	EOAI3402143		DUB
	EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction and apoptotic sensitization of Usp5 knockdown and fully blocks melanoma tumor growth.		DUB
T3661	Citarinostat	ACY241,HDAC-IN-2	HDAC
	ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...		HDAC
T3633	Crenigacestat	LY3039478	Gamma-secretase
	Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor mo...		Gamma-secretase
T6844	GGTI298 Trifluoroacetate	GGTI 298,GGTI 298 TFA salt	Apoptosis , Transferase , Ras
	GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis.		Apoptosis , Transferase , Ras
T17187	TZ9		Apoptosis , E1/E2/E3 Enzyme
	TZ9 is a selective and potent Rad6 inhibitor with anticancer and anti-tumor activity.TZ9 inhibits Rad6B-induced ubiquitination of histone H2A.TZ9 induces cell cycle arrest and apoptosis.		Apoptosis , E1/E2/E3 Enzyme
T1535	Sodium 4-phenylbutyrate	Sodium Phenylbutyrate,Buphenyl,TriButyrate	Apoptosis , HDAC , Autophagy
	Sodium 4-phenylbutyrate (TriButyrate), a transcriptional regulator, reversibly inhibits class I and II histone deacetylases (HDACs )resulting in a global increase in gene expression, decreased cellular proliferation, inc...		Apoptosis , HDAC , Autophagy
T23479L	TT-232 TFA（147159-51-1 free base）		Others
	TT2-32 TFA induces a biphasic activation of phosphotyrosine phosphatase activity in human colon tumor cell line, SW620		Others
T27094	CT-2584	CT2584,CT 2584	Reactive Oxygen Species
	CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types. CT-2584 re...		Reactive Oxygen Species
T17208	USL311		CXCR
	USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing...		CXCR
T2576	Brivanib (alaninate)	BMS-582664,Brivanib Alaninate	VEGFR , FGFR , Autophagy
	Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosi...		VEGFR , FGFR , Autophagy
T60839	SLMP53-1		p53
	SLMP53-1 is a p53 activator with anti-tumor activity, inhibits wt and mutp53, activates reprogramming of glucose metabolism in xenografted human tumor tissues, and interferes with angiogenesis and migration. SLMP53-1 inh...		p53
T39078	CXCR7 antagonist-1	CXCR7 antagonist-1	CXCR
	CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cell proliferation and tumor formation and can be used in stud...		CXCR
T12896L	Shepherdin 79-87 acetate	Shepherdin 79-87 acetate (861224-28-4 free base)	HSP , Survivin
	Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.		HSP , Survivin
T6864	Ixabepilone	BMS 247550,Ixempra,Azaepothilone B,BMS 247550-1	Apoptosis , Microtubule Associated
	Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell ...		Apoptosis , Microtubule Associated
T63788	PCLX-001		Others
	PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstra...		Others
TQ0141	Taltobulin	HTI-286,SPA-110	Apoptosis , Microtubule Associated
	Taltobulin (HTI-286) is a synthetic analog of the tripeptide cysteine, a microtubule protein inhibitor that inhibits liver tumor cell proliferation in vitro and tumor growth in vivo.Taltobulin is cytotoxic, induces mitot...		Apoptosis , Microtubule Associated

Compounds

Target: DNA/RNA Synthesis

DM1-SMe

T21408

Synonym: DM1-SSMe

Target: Microtubule Associated

Phthalazinone pyrazole

T21981

Synonym:

Target: Aurora Kinase

Synonym: TLR7 agonist T7

Target: TLR

Regorafenib monohydrate

T1792L

Synonym:

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Uzansertib phosphate

T12477

Synonym: INCB053914 phosphate

Target: Pim

Pixantrone dimaleate

T2394

Synonym: BBR-2778,Pixantrone Maleate,BBR 2778 dimaleate

Target: Topoisomerase

PKCβ inhibitor 1

T8376

Synonym: KUN79359

Target: Apoptosis, PKC

PND-1186

T1950

Synonym: PND1186,PND 1186,VS-4718,SR-2516

Target: Apoptosis, FAK

Regorafenib

T1792

Synonym: BAY 73-4506,Fluoro-Sorafenib

Target: Raf, VEGFR, c-RET, PDGFR, c-Kit, Autophagy

Erlotinib

T0373

Synonym: OSI-744,NSC 718781,CP358774,R1415

Target: EGFR, Autophagy

ADH-1 trifluoroacetate

T1608

Synonym: Exherin trifluoroacetate

Target: Dehydrogenase

Target: VEGFR, c-Met/HGFR

XL413

T3352

Synonym:

Target: cholecystokinin, Casein Kinase, Pim, CDK

Lexibulin

T2090

Synonym: CYT-997

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated

6-HYDROXYLAMINOURACIL

Synonym: CC223,CC 223,CC-223

Target: Apoptosis, c-Fms, DNA-PK, FLT, PI3K, mTOR

BMS-599626 2HCL(714971-09-2 Free base)

T2610L

Synonym: BMS 599626 dihydrochloride,BMS-599626 2HCL(714971-09-2 Free base),AC480 2HCl

Target: PAI-1, Apoptosis

Probimane

T3485

Synonym: AT-2153,MM-159

Target: Others

RMC-9805

T78212

Synonym: KRAS G12D inhibitor 18,KRAS G12D IN 18

Target: Apoptosis, PI3K

Synonym: ACY241,HDAC-IN-2

Target: Gamma-secretase

GGTI298 Trifluoroacetate

T6844

Synonym: GGTI 298,GGTI 298 TFA salt

Target: Apoptosis, Transferase, Ras

TZ9

T17187

Synonym:

Target: Apoptosis, E1/E2/E3 Enzyme

Sodium 4-phenylbutyrate

T1535

Synonym: Sodium Phenylbutyrate,Buphenyl,TriButyrate

Target: Apoptosis, HDAC, Autophagy

TT-232 TFA（147159-51-1 free base）

Synonym: CT2584,CT 2584

Target: Reactive Oxygen Species

Synonym: BMS-582664,Brivanib Alaninate

Target: VEGFR, FGFR, Autophagy

Synonym: CXCR7 antagonist-1

Target: CXCR

Shepherdin 79-87 acetate

T12896L

Synonym: Shepherdin 79-87 acetate (861224-28-4 free base)

Target: HSP, Survivin

Ixabepilone

T6864

Synonym: BMS 247550,Ixempra,Azaepothilone B,BMS 247550-1

Target: Apoptosis, Microtubule Associated

Synonym: HTI-286,SPA-110

Target: Apoptosis, Microtubule Associated

カタログ番号	製品名	別名	ターゲット
T13818	Phytohemagglutinin	PHA-M	Apoptosis
	Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity		Apoptosis
T5808	(-)-Oxypeucedanin hydrate	OXYPEUCEDANIN HYDRATE	Others
	(-)-Oxypeucedanin hydrate is a furanocoumarin. It has a role as a metabolite.		Others
TN2132	Quinizarin	1,4-Dihydroxyanthraquinone	Others , DNA/RNA Synthesis , Antifungal
	Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product		Others , DNA/RNA Synthesis , Antifungal
T1032	Erythromycin	E-Mycin	ribosome , Antibacterial , Antibiotic
	Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.		ribosome , Antibacterial , Antibiotic
T1511	Daunorubicin hydrochloride	Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin	Apoptosis , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic , Autophagy
	Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein synthesis.
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
T32291	Jineol	NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081	Others
	Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.		Others
TN1017	Physion 8-O-β-D-glucoside	Physcion 1-O-beta-D-glucoside	Others
	Physion 8-O-β-D-glucoside is a tumor cell growth inhibitor.		Others
T0421	I-Inositol	Inositol,myo-Inositol,meso-Inositol	Endogenous Metabolite
	i-Inositol (myo-Inositol) is a intracellular phosphate compound, involved in cell signaling and may stimulate tumor cell differentiation.		Endogenous Metabolite
T4863	DL-Homocysteine	2-Amino-4-mercaptobutyric acid	Endogenous Metabolite
	DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.		Endogenous Metabolite
T3524	Halofuginone hydrobromide	Tempostatin,RU-19110 (hydrobromide),Stenorol	Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T6290	Tanespimycin	17-AAG,CP 127374,NSC 330507,KOS 953	Apoptosis , Mitophagy , HSP , Antibacterial , Antibiotic , Autophagy
	Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
T0968	Paclitaxel	Taxol,NSC 125973	Apoptosis , Microtubule Associated , Autophagy
	Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.		Apoptosis , Microtubule Associated , Autophagy
T4S1024	Picfeltarraenin IB		Others , AChE
	1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.		Others , AChE
T2336	Vitamin K2	Menatetrenone	Endogenous Metabolite
	Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases, thereby affecting several...		Endogenous Metabolite
T2S0886	Terrestrosin D		Apoptosis , Others
	Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of action...		Apoptosis , Others
TN1445	Bisabolangelone		p38 MAPK , MAPK
	Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.		p38 MAPK , MAPK
T5S1882	Songorine	Napellonine,Zongorine,Bullatine G	Others , GABA Receptor
	Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.		Others , GABA Receptor
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
TN1373	α-Humulene	Alpha-caryophyllene	TNF , NOS , COX
	α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an...		TNF , NOS , COX
T2220	2-Methoxyestradiol	NSC-659853,2-MeOE2,2-ME2	Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
	2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
TN1560	Dehydroeffusol	5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol	MMP , ERK , GPR , Others
	Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reti...		MMP , ERK , GPR , Others
T0190	Vinorelbine	KW-2307 base	Microtubule Associated
	Vinorelbine (KW-2307 base) is a semisynthetic vinca alkaloid. Vinorelbine binds to tubulin and prevents the formation of the mitotic spindle, resulting in the arrest of tumor cell growth in metaphase.		Microtubule Associated
TN7052	Crocin III	Crocetin-mono-(β-D-gentiobiosyl)-ester	Others
	Crocin III (Crocetin-mono-(β-D-gentiobiosyl)-ester) is a crocin derived from saffron (Crocus sutivus L.). Crocins inhibit the cell growth of tumor cells and have anti-inflammatory activity.		Others
T6062	Brefeldin A	BFA,Ascotoxin,Cyanein,Decumbin	ATPase , Mitophagy , Antibiotic , Autophagy , HSV , CRISPR/Cas9
	Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation and apoptosis, and also possesses autophagy inhibitory activ...
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T1086	Vitamin D2	Calciferol,Ergocalciferol,Ercalciol	DNA/RNA Synthesis , Endogenous Metabolite
	Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in...		DNA/RNA Synthesis , Endogenous Metabolite
T3314	Perillyl alcohol	Isocarveol,Perilla alcohol	Apoptosis , Endogenous Metabolite
	Perillyl Alcohol is a naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol (Isocarveol) inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-...		Apoptosis , Endogenous Metabolite
T1257	Bestatin	Ubenimex	Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
	Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...		Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
T6S1784	Brazilin	Natural Red 24,Braziletto,Brasilin,Superbresiline	Apoptosis , Others , AMPK , Autophagy
	1. Brazilin (Braziletto) exhibits anti-hepatotoxic, antiplatelet effects. 2. Brazilin has cancer preventive effect, may inhibit T24 cell growth and trigger cell death through a c-Fos-mediated and tumor cell specific sign...		Apoptosis , Others , AMPK , Autophagy
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
T5S0993	Kurarinone		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
	Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli...		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
T4S1615	Sanggenon C	Sanggenone C	NF-κB
	1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO pro...		NF-κB
TN3628	Chamaejasmenin B		Others
	Chamaejasmenin B is a compound isolated from Stellera chamaejasme L. Chamaejasmenin B has anticancer and antitumor activity, inhibiting cancer cell migration and invasion, and inhibiting tumor metastasis.Chamaejasmenin B...		Others
T2897	(Rac)-Shikonin	(±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid	Others
	(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...		Others
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
T36715	Tetrac	Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid	Apoptosis , EGFR
	Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac...		Apoptosis , EGFR
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T7961	N4-Benzoyl-2′-deoxycytidine		Others
	N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, b...		Others
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T75643	Isoxanthohumol		HSV
	Isoxanthohumol is a prenylated flavonoid derived from hops and beer with antiproliferative activity against several human cancer cell lines.Isoxanthohumol inhibits the metastasis or invasion of lung metastases of tumor c...		HSV
TN1620	Eriocalyxin B		Apoptosis , cAMP , NF-κB , STAT
	Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inh...		Apoptosis , cAMP , NF-κB , STAT
T6S1256	Ruscogenin		NOS , NF-κB , NOD-like Receptor (NLR)
	1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...		NOS , NF-κB , NOD-like Receptor (NLR)
T4958	(-)-Alkannin	Alkannin,Shikonin	Apoptosis , PI3K
	(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a...		Apoptosis , PI3K
T2823	Crocin	Gardenia Yellow,Alpha-Crocin	Others
	Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...		Others
T3339	Sophoridine	5-Epidihydrosophocarpine,Dihydro-5-episophocarpine	Apoptosis , Topoisomerase
	Sophoridine (Dihydro-5-episophocarpine), a natural anticancer drug, has been used in China for decades. A series of novel N-substituted Sophoridinic acid derivatives were synthesized and evaluated for their cytotoxicity ...		Apoptosis , Topoisomerase
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天然物製品

(-)-Oxypeucedanin hydrate

T5808

Synonym: OXYPEUCEDANIN HYDRATE

Target: Others

Quinizarin

TN2132

Synonym: 1,4-Dihydroxyanthraquinone

Target: Others, DNA/RNA Synthesis, Antifungal

Erythromycin

T1032

Synonym: E-Mycin

Target: ribosome, Antibacterial, Antibiotic

Daunorubicin hydrochloride

T1511

Synonym: Daunomycin HCl,RP-13057 Hydrochloride,Rubidomycin hydrochloride,Daunorubicin HCl,Daunomycin

Target: Apoptosis, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic, Autophagy

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Jineol

T32291

Synonym: NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081

Target: Others

Physion 8-O-β-D-glucoside

TN1017

Synonym: Physcion 1-O-beta-D-glucoside

Target: Others

i-Inositol

T0421

Synonym: Inositol,myo-Inositol,meso-Inositol

Target: Endogenous Metabolite

DL-Homocysteine

T4863

Synonym: 2-Amino-4-mercaptobutyric acid

Target: Endogenous Metabolite

Halofuginone hydrobromide

T3524

Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Tanespimycin

T6290

Synonym: 17-AAG,CP 127374,NSC 330507,KOS 953

Target: Apoptosis, Mitophagy, HSP, Antibacterial, Antibiotic, Autophagy

Paclitaxel

T0968

Synonym: Taxol,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy

Synonym: Menatetrenone

Target: Endogenous Metabolite

Terrestrosin D

T2S0886

Synonym:

Target: Apoptosis, Others

Bisabolangelone

TN1445

Synonym:

Target: p38 MAPK, MAPK

Songorine

T5S1882

Synonym: Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Dauricine

T6S0119

Synonym:

Target: Apoptosis, Others, NF-κB

Cnidicin

TN1516

Synonym:

Target: NOS, NO Synthase

α-Humulene

TN1373

Synonym: Alpha-caryophyllene

Target: TNF, NOS, COX

2-Methoxyestradiol

T2220

Synonym: NSC-659853,2-MeOE2,2-ME2

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy

Dehydroeffusol

TN1560

Synonym: 5-Ethenyl-1-Methylphenanthrene-2,7-Diol,Dehydro Effusol

Target: MMP, ERK, GPR, Others

Vinorelbine

T0190

Synonym: KW-2307 base

Target: Microtubule Associated

Crocin III

TN7052

Synonym: Crocetin-mono-(β-D-gentiobiosyl)-ester

Target: Others

Brefeldin A

T6062

Synonym: BFA,Ascotoxin,Cyanein,Decumbin

Target: ATPase, Mitophagy, Antibiotic, Autophagy, HSV, CRISPR/Cas9

Cytochalasin D

T3229

Synonym:

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Hederacolchiside A1

T2P2806

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Vitamin D2

T1086

Synonym: Calciferol,Ergocalciferol,Ercalciol

Target: DNA/RNA Synthesis, Endogenous Metabolite

Perillyl alcohol

T3314

Synonym: Isocarveol,Perilla alcohol

Target: Apoptosis, Endogenous Metabolite

Bestatin

T1257

Synonym: Ubenimex

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

Brazilin

T6S1784

Synonym: Natural Red 24,Braziletto,Brasilin,Superbresiline

Target: Apoptosis, Others, AMPK, Autophagy

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Timosaponin AIII

T3395

Synonym: Filiferin B,AneMarsaponin A3,Timosaponin A3

Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT

Sanggenon C

T4S1615

Synonym: Sanggenone C

Synonym: (±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid

Target: Beta Amyloid, Others

Tetrac

T36715

Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid

Target: Apoptosis, EGFR

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: MMP, Others

N4-Benzoyl-2′-deoxycytidine

Synonym: Flavokavain A

Target: Apoptosis, p38 MAPK

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: Apoptosis, cAMP, NF-κB, STAT

Ruscogenin

T6S1256

Synonym:

Target: NOS, NF-κB, NOD-like Receptor (NLR)

(-)-Alkannin

T4958

Synonym: Alkannin,Shikonin

Target: Apoptosis, PI3K

Crocin

T2823

Synonym: Gardenia Yellow,Alpha-Crocin

Target: Others

Sophoridine

T3339

Synonym: 5-Epidihydrosophocarpine,Dihydro-5-episophocarpine

Target: Apoptosis, Topoisomerase

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01391	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the accession number is Q9WU72.
TMPJ-00603	TL1A/TNFSF15 Protein, Mouse, Recombinant	Mouse	E. coli
	Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPJ-01434	BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 38-45 KDa and the accession number is G7Q0I4.
TMPJ-01446	BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 12 and 15-20 KDa and the accession number is G7Q0I4.
TMPJ-00066	BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane...
TMPJ-00920	CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)	Mouse	HEK293 Cells
	CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and ...
TMPJ-00281	CADM1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPJ-00421	CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I ...
TMPJ-00204	TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointesti...
TMPJ-00206	TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)	Human	HEK293 Cells
	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointesti...
TMPJ-00205	TROP-2 Protein,Human,Recombinant (aa 88-274, hFc）	Human	HEK293 Cells
	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointesti...
TMPJ-00634	CD40 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
TMPJ-01420	CD40 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	CD40 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-70 KDa and the accession number is XP_005569275.1.
TMPJ-00178	BAFF/TNFSF13B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accession number is Q9Y275.
TMPJ-00615	CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus	HEK293 Cells
	CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7BYS2.
TMPJ-00616	CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40 KDa and the accession number is F7BYS2.
TMPH-01002	BCAP31 Protein, Human, Recombinant (GST)	Human	E. coli
	BCAP31 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.5 kDa and the accession number is P51572.
TMPJ-00152	CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is 23-28 KDa and the accession number is P29965.
TMPJ-00151	CD40 Ligand Protein, Human, Recombinant	Human	E. coli
	CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00150	CD40 Ligand Protein, Human, Recombinant (Mammalian)	Human	HEK293 Cells
	CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
TMPJ-00153	CD40 Ligand Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa and the accession number is P29965.
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPJ-00177	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated	Human	HEK293 Cells
	B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), T...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-03382	FGF-6 Protein, Human, Recombinant	Human	E. coli
	FGF6, also known as FGF-6, belongs to the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, includi...
TMPK-00176	BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (...
TMPJ-00090	FGF-9 Protein, Human, Recombinant	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inc...
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPY-00476	ITGB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293 Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T...
TMPY-02483	ATP citrate lyase/ACLY Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP...
TMPY-04722	DcR1/TRAILR3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ...
TMPY-03104	FGF-17 Protein, Human, Recombinant	Human	E. coli
	FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including ...
TMPK-00807	Osteopontin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ...
TMPJ-01465	GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-00817	Granzyme B/GZMB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-02907	FGF-19 Protein, Human, Recombinant	Human	E. coli
	FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)	Human	HEK293 Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-02525	RGMA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His)	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPY-00365	GALNT7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPY-04329	Vimentin Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers ...
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BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)

TMPJ-01391

Species: Mouse

Expression System: HEK293 Cells

TL1A/TNFSF15 Protein, Mouse, Recombinant

TMPJ-00603

Species: Mouse

Expression System: E. coli

BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)

TMPJ-01434

Species: Cynomolgus

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)

TMPJ-01446

Species: Cynomolgus

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)

TMPJ-00066

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)

TMPJ-00920

Species: Mouse

Expression System: HEK293 Cells

CADM1 Protein, Mouse, Recombinant (hFc)

TMPJ-00281

Species: Mouse

Expression System: HEK293 Cells

CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)

TMPJ-00421

Species: Human

Expression System: HEK293 Cells

TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00204

Species: Human

Expression System: HEK293 Cells

TROP-2 Protein, Human, Recombinant (aa 27-274, hFc)

TMPJ-00206

Species: Human

Expression System: HEK293 Cells

TROP-2 Protein,Human,Recombinant (aa 88-274, hFc）

TMPJ-00205

Species: Human

Expression System: HEK293 Cells

CD40 Protein, Cynomolgus, Recombinant (His)

TMPJ-00634

Species: Cynomolgus

Expression System: HEK293 Cells

CD40 Protein, Cynomolgus, Recombinant (hFc)

TMPJ-01420

Species: Cynomolgus

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (His)

TMPJ-00178

Species: Human

Expression System: HEK293 Cells

CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00615

Species: Rhesus

Expression System: HEK293 Cells

CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)

TMPJ-00616

Species: Rhesus

Expression System: HEK293 Cells

BCAP31 Protein, Human, Recombinant (GST)

TMPH-01002

Species: Human

Expression System: E. coli

CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00152

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Human, Recombinant

TMPJ-00151

Species: Human

Expression System: E. coli

CD40 Ligand Protein, Human, Recombinant (Mammalian)

TMPJ-00150

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Human, Recombinant (His & Flag)

TMPJ-00153

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (His)

TMPJ-00160

Species: Human

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated

TMPJ-00177

Species: Human

Expression System: HEK293 Cells

TGF alpha Protein, Human, Recombinant

TMPY-03958

Species: Human

Expression System: E. coli

FGF-6 Protein, Human, Recombinant

TMPY-03382

Species: Human

Expression System: E. coli

BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00176

Species: Human

Expression System: HEK293 Cells

FGF-9 Protein, Human, Recombinant

TMPJ-00090

Species: Human

Expression System: E. coli

TNF alpha Protein, Rabbit, Recombinant

TMPJ-00779

Species: Rabbit

Expression System: E. coli

ITGB1 Protein, Human, Recombinant (His)

TMPY-00476

Species: Human

Expression System: HEK293 Cells

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus Insect Cells

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TMPJ-00249

Species: Human

Expression System: HEK293 Cells

CEACAM3 Protein, Human, Recombinant (His)

TMPY-01850

Species: Human

Expression System: HEK293 Cells

TPSAB1 Protein, Human, Recombinant (His)

TMPJ-01204

Species: Human

Expression System: HEK293 Cells

ATP citrate lyase/ACLY Protein, Human, Recombinant (His)

TMPY-02483

Species: Human

Expression System: Baculovirus Insect Cells

DcR1/TRAILR3 Protein, Human, Recombinant (His)

TMPY-04722

Species: Human

Expression System: HEK293 Cells

FGF-17 Protein, Human, Recombinant

TMPY-03104

Species: Human

Expression System: E. coli

Osteopontin Protein, Mouse, Recombinant (His)

TMPK-00807

Species: Mouse

Expression System: HEK293 Cells

GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)

TMPJ-01465

Species: Human

Expression System: E. coli

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

Granzyme B/GZMB Protein, Human, Recombinant (His)

TMPY-00817

Species: Human

Expression System: HEK293 Cells

FGF-19 Protein, Human, Recombinant

TMPY-02907

Species: Human

Expression System: E. coli

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

VEGF121 Protein, Human, Recombinant (His)

TMPJ-00865

Species: Human

Expression System: HEK293 Cells

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TMPJ-01464

Species: Human

Expression System: HEK293 Cells

RGMA Protein, Human, Recombinant (His)

TMPY-02525

Species: Human

Expression System: HEK293 Cells

CD16a Protein, Human, Recombinant (F176V, His)

TMPY-01964

Species: Human

Expression System: HEK293 Cells

GALNT7 Protein, Human, Recombinant (His)

TMPY-00365

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

TMPJ-01467

Species: Human

Expression System: E. coli

Vimentin Protein, Human, Recombinant (His)

TMPY-04329

Species: Human

Expression System: Baculovirus Insect Cells

--------- More ---------

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